Learn more about StatPlus for Windows or StatPlus:mac. StatPlus comes as both standalone spreadsheet and Excel add-in, and works on Windows and Mac OS. The determined parameter of acute toxicity of OHFS is closeĥ0 values of other hexafluorosilicates known from the literature relative safety and high caries-prophylactic and periodontal-protective efficacies of OHFS indicate the prospects for further studies of this compound. StatPlus includes all the BioStat features and even more: design of experiment, time series analysis and forecasting, control charts for quality control. The results of determining the toxicometric characteristics of octenidine hexafluorosilicate in rats by oral administration allow to classify this compound as moderately toxic substances Extrapolation to humans of acute toxicity parameters obtained in animals was determined using the coefficient of resistance to the species and is 132.15 mg/kg body weight.Ĭonclusions. The range of possible applications of StatPlus 2009 is virtually unlimited - sociology, financial analysis, biostatistics, economics, insurance industry. Hazard values of octenidine hexafluorosilicate show that it does not pose a particular danger to humans. Pose a high potential risk of the onset and development of poisoning. The variability of lethal doses, the studied hexafluorosilicate can be attribute to compounds that do not The results of the acute toxicity determination of octenidine hexafluorosilicate show that this compound, in the oral route of administration, belongs to the III class of toxicityįor the human (slightly hazardous) and to the IV class of toxicity for the animals (white rats).
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Results was carry out using the “StatPlus 2009” software (AnalystSoft, USA, 2009). Index and the S-function angle of inclination (variability of lethal doses). In addition, the following hazard indicators were calculated: 1/LD50 - the median lethal dose (absolute toxicity), LD84/LD16 - the range of lethal doses (zone of acute toxic effect), 1/(LD50-S) - the total toxicity It comes with a comprehensive set of tools and functions not.
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The main criterion for quantifying the toxicity ofĥ0, which was determined using the least squares method. StatPlus 2009 Professional is an application that assists users in processing statistical data. Out on 42 male Wistar rats weighing 180–200 grams. A study of the acute toxicity of octenidine hexafluorosilicate was carry
Determination of toxicometric characteristics of octenidine hexafluorosilicate (OHFS), characterized by significant pharmaceutical potential, in an acute experiment on rats by
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